Table 4.
The disease association of iLOCi selected genes from gene-only SNP analyses
| Disease | # iLOCi genes in top 1000 SNP pairs | Reported in WTCCC single SNP analyses |
Reported in HuGE Navigator database | ||
|---|---|---|---|---|---|
| # Analyzed genes (# SNPs) |
# iLOCi genes | # Analyzed genes (# SNPs) |
# iLOCi genes | ||
| BD | 654 | 42 (1757) | 8 | 665 (16598) | 52 |
| CAD | 710 | 29 (2097) | 3 | 735 (11564) | 37 |
| CD | 279 | 54 (1651) | 4 | 531 (7181) | 10 |
| HT | 595 | 32 (3164) | 19 | 1240 (22004) | 64 |
| RA | 677 | 34 (822) | 4 | 503 (5902) | 19 |
| T1D | 687 | 39 (1153) | 5 | 512 (6924) | 29 |
| T2D | 486 | 29 (1289) | 5 | 2456 (41244) | 110 |
The table displays the number of previously reported disease-associated genes which were found in all analyzed genes and in the set of genes involved in top 1000 interaction pairs. The reported disease genes are shown for both the genes associated with disease SNPs from WTCCC paper [3] and the ones reported in HuGE Navigator database [33].