Table 1.
Prevalence of sickle cell disease and sickle cell trait
| Author | Publication year | Location | Relevance | Period | N | Hb AS | Hb SS |
| Brandalise S(12) | 2004 | Campinas - SP | High | 1992-2000 | 281.884 | 1.98% | 10.3/100.000 |
| Diniz D(2) | 2009 | Distrito Federal | High | 2004-2006 | 116.271 | 3.23% | 90/100.000 |
| Pinheiro SL(3) | 2006 | Fortaleza - CE | Low | 2001-2002 | 389 | 3.85% | 257/100.000 |
| Holsbach DR(15) | 2008 | Mato Grosso do Sul | High | 2000-2005 | 190.809 | 1.64% | 10.5/100.000 |
| Araújo MCPE (6) | 2004 | Natal - RN | Low | 2001 | 1940 | 1.50% | 51.5/100.000 |
| WatanabeAM (10) | 2008 | Paraná | High | 2002-2004 | 548.810 | 1.52% | 2.2/100.000 |
| Sommer CK (5) | 2006 | Rio Grande do Sul | High | 2003-2004 | 117.320 | 1.14% | 0.85/100.000 |
| Magalhães PKR(9) | 2009 | Ribeirão Preto - SP | High | 2002-2005 | 103.021 | 2.60% | 14.6/100.000 |
| Lobo CLC (4) | 2003 | Rio de Janeiro - RJ | Medium | 2000-2001 | 99.260 | 3.96% | 60.5/100.000 |
| Adomo EV (16) | 2005 | Salvador - BA | Low | 2000 | 581 | 9.80% | 172/100.000 |
| Ducatti RP(14) | 2001 | S. José do Rio Preto - SP | Low | 1997-1998 | 913 | 3.72% | NR |
| Pultrini T(13) | 2004 | Western São Paulo State | Medium | 2001-2003 | 72.510 | 2.35% | 4.1/100.000 |
NR = Not reported; N = number of newborns evaluated