Table 1.
Important characteristics of studies included in the meta-analysis
| First author | Year | Type of study | Number of patients | Number of patients with data on negative margins | Age | Subastratification of margins | Duration of follow up |
|---|---|---|---|---|---|---|---|
| Muratore et al. | 2009 | Retrosepective, January 1999 to December 2007 | 314 | 259 | Mean age 62.8 years (95 % CI 61.7–63.9) | Negative <=1 cm, Negative >1 cm | Mean- 39.8 months |
| Vandeweyer et al. | 2009 | Retrospective, February 1992 to December 2007 | 261 | 194 | Median age 64 years | Positive, 0-1 mm, >1 mm-<4, 4-<10 mm, >=10 mm | Median - 4.7 years |
| Nuzzo et. al | 2008 | Retrospective study from a Prospective database, January 1992–December 2005 | 185 | 174 | Mean age 61 years (range 32–81 years) | Positive, Negative( <=2 mm, 3-5 mm, 6-9 mm, >=10 mm) | Mean - 39 months |
| Wakai et. al | 2008 | Retrospective, January 1989–December 2004 | 90 | 80 | Median age 64 years (range 32–80 years) | 0 (Positive), <1 cm, >=1 cm | Median - 127 months |
| Hamady ZZR et al. | 2006 | Retrospective, January 1993 and December 2001 | 293 | 187 | Mean age 61 years (range 38–80 years) | Positive, Negative (=1 mm vs >1 mm, 1–2 mm vs >2 mm, 1–5 mm vs >5 mm, 1–10 mm vs. >10 mm | Minimum −29 months |
| Kokudo et al. | 2002 | Retrospective, January1, 1980 to December 31, 2000 | 194 | 183 | Mean age 59 years (range 35 to 82 years) | Negative <2 mm, 2–4 mm, 5–9 mm and >=10 mm) | Median −29.1 months |
| Minagawa et. al. | 2000 | Retrospective 1980 to 1997 | 235 | 145 | Median age 59.2 years (range 30–80 years) | Unknown, <1 cm, >=1 cm | Median −28 months, mean- 43 months |
| Iwatsuki et al. | 1999 | Retrospective, Year 1981 to 1996 | 305 | 277 | Mean ± S.E. (60 ± 0.6 years) range 26 to 82 years | Positive (involved), >1 cm, <=1 cm | Median - 32 months |
| Scheele et al. | 1995 | Retrospective, 1960 to 1992 | 434 | 350 | Median age 59 years (range 26–91 years) | 1–9 mm, >=10 mm | All patients followed up to Nov of 1993. Median duration of follow up not specified |
| Cady et al. | 1992 | 142 | 58 | Median 61 years (range 31–80 years) | Positive, Negative >=1 cm, Negative < 1 cm, unknown | Minimum - 12 months | |
| van Ooijen et al. | 1991 | Retrospective, 1979 to 1989 | 118 | 82 | Median age 57 (range 28–83 years) | Positive, <1 cm, >1 cm | Median - 18 months |