Table 2.
Summary of data on disease free survival for studies included in the meta-analysis
| < 1 cm | ≥ 1 cm | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| First author | Patients with data on negative margins | n | One-year DFS (%) | Three-year DFS (%) | Five-year DFS (%) | n | One-year DFS (%) | Three-year DFS (%) | Five-year DFS (%) |
| Muratore et al. | 259 | 175 | – | 30.2 | 23.5 | 84 | – | 37.3 | 28.2 |
| Vandeweyer et al. | 194 | 107 | 58 | 28 | 20 | 87 | 64 | 41 | 29 |
| Nuzzo et. ala | 174 | 64 | – | – | 11.4 | 110 | – | – | 41.6 |
| Wakai et. al | 80 | 51 | – | – | 19 | 29 | – | – | 40 |
| Hamady ZZR et al. | 187 | 129 | – | – | 28 | 58 | – | – | 31 |
| Kokudo et al.a | 183 | 134 | 62 | 34.2 | 24.3 | 49 | 78.3 | 50.1 | 50.1 |
| Minagawa et. al. | 145 | 118 | – | 30 | 24 | 27 | – | 27 | 27 |
| Iwatsuki et al. | 277 | 147 | – | 30.2 | 22.5 | 130 | – | 38.5 | 28.9 |
| Scheele et al. | 350 | 204 | – | 38 | 28 | 146 | – | 46 | 33 |
| Cady et al. | 58 | 33 | – | – | 18 | 25 | – | – | 50 |
| van Ooijen et al. | 82 | 38 | – | – | 13 | 44 | – | – | 20 |
a For these studies different sub-centimeter sub-categories were pooled to compute percentage survival for “< 1 cm subgroup”