. Author manuscript; available in PMC: 2013 Jun 1.

Published in final edited form as: Circ Cardiovasc Genet. 2012 Apr 24;5(3):293–300. doi: 10.1161/CIRCGENETICS.111.961136

Table 1.

Multiple logistic regression analysis reveals a significant association between maternal age and the incidence of membranous and muscular VSD in Nkx2-5^+/- animals from the C57Bl/6 X FVB/N F2 population. Each month of maternal aging is associated with a small increase in risk. The effect of paternal age or litter size is of questionable or marginal significance

Factor	Membranous VSD			Muscular VSD
Factor	OR	95% CI	P	OR	95% CI	P
Maternal age, months	1.11	1.05-1.17	1.7 × 10^-4	1.22	1.09-1.38	8.5 × 10^-4
Paternal age, months	0.98	0.94-1.03	NS	0.89	0.79-0.99	0.043
Litter size, N	0.948	0.880-1.000	0.051	1.036	0.932-1.147	NS

OR, odds ratio. CI, confidence interval. NS, not significant.