Table 2.

Results of gene-based association tests using VEGAS with 10⁷ permutations.

Chromosome	Gene	N	Start (bp)	Stop (bp)	Test statistic	P-value
19	ZNF431	5	21,116,679	21,160,645	63.955	<10−7
19	ZNF714	2	21,056,810	21,099,723	34.681	<10−7
11	B3GAT1	6	133,753,607	133,787,022	62.712	<10−7
11	GLB1L2	5	133,707,018	133,751,428	57.138	<10−7
8	CSMD1	19	2,780,281	4,839,736	101.600	<10−7
16	CDH13	10	81,218,078	82,387,700	53.829	<10−6
11	CNTN5	19	98,397,080	99,732,683	119.099	<10−6
11	GLB1L3	5	133,651,484	133,694,668	57.138	<10−6
9	PTPRD	19	8,304,245	10,602,509	104.050	<10−6
2	CTNNA2	7	79,593,633	80,729,416	43.953	<10−6
20	CDH4	10	59,260,953	59,945,694	54.390	2 × 10−6
1	CSMD2	18	33,752,195	34,404,030	132.064	2 × 10−6
5	AP3B1	2	77,333,905	77,626,284	26.100	3 × 10−6
8	SULF1	10	70,541,412	70,735,701	71.135	4 × 10−6
7	DNAH11	9	21,549,357	21,907,982	59.205	4 × 10−6
5	ARHGAP26	6	142,130,475	142,588,765	57.388	4 × 10−6
12	TMEM132D	17	128,122,223	128,954,165	105.118	5 × 10−6
16	A2BP1	12	6,009,132	7,702,500	59.851	7 × 10−6
10	CAMK1D	11	12,431,588	12,911,739	57.470	7 × 10−6
1	FMN2	8	238,321,807	238,705,112	49.759	7 × 10−6
19	KANK2	10	11,135,945	11,167,496	73.331	9 × 10−6
11	OPCML	13	131,790,084	132,907,613	67.945	1.1 × 10−5
3	RBMS3	11	29,297,946	30,021,624	76.673	1.4 × 10−5
9	ASTN2	9	118,227,327	119,217,138	54.474	1.5 × 10−5
7	CNTNAP2	26	145,444,385	147,749,019	160.697	1.6 × 10−5
5	LHFPL2	8	77,816,793	77,980,404	102.079	1.6 × 10−5
9	ABCA1	3	106,583,104	106,730,257	30.986	1.7 × 10−5
8	SGCZ	26	13,991,743	15,140,163	147.671	1.7 × 10−5
20	PLCB1	9	8,061,295	8,813,547	48.709	1.9 × 10−5
6	FARS2	13	5,206,582	5,716,815	87.725	1.9 × 10−5

VEGAS: Versatile Gene-based Association Study. N: Total number of SNPs; bp: Base pair; SNP: Single Nucleotide Polymorphism.