Fig. 1.
Identification of a quercetin responsive region between nt −800 and −549 in the PAI-1 promoter. A: Schematic representation of the luciferase reporter constructs containing the pPAI-800/luc, pPAI-549/luc, and pPAI-308/luc) of human PAI-1 promoter. B: ECs transiently transfected with pPAI-800/luc, pPAI-549/luc, and pPAI-308/luc were treated with quercetin or vehicle for 6 h. The columns and vertical bar represent means ± SE of five separated replicates; *P ≤ 0.05.