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. 2012 Dec 13;7(12):e51655. doi: 10.1371/journal.pone.0051655

Figure 2. Resveratrol inhibits PC-3M-MM2 cell migration and invasiveness. A, B,

Figure 2

Wound healing assays were performed on cells treated with vehicle or resveratrol (25 and 50 µM) for 24 h. Resveratrol significantly inhibited the migration of cells into the denuded areas, as indicated by double arrows (A) and in the bar diagram (B). C, D, Modified Boyden invasion chamber assay showed that resveratrol (25 and 50 µM) treatment for 24 h significantly inhibited PC-3M-MM2 cell invasion as indicated by red arrow (C). Representative images of the invasive cells per treatment group are shown. Data presented in the bar diagram (B, D) is mean±SEM of at least 3 independent experiments. Asterisk (*) indicates statistically significant difference (p<0.05) from vehicle-treated cells.