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. 2012 Dec 13;7(12):e51709. doi: 10.1371/journal.pone.0051709

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© 2012 Cao et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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A,B: effects of chronic exercise. C,D: effects of acute exercise. Values are means ± SE. ^** P<0.01 vs. the control group; ^§ P<0.05 vs. the HFD+STZ group; ^‡ P<0.05 and ^‡‡ P<0.01 vs. the HFD+STZ group. PGC1α: peroxisome proliferator-activated receptor-γ coactivator; NRF1: nuclear respiratory factor 1; CON: control; HFD: high-fat diet; STZ, streptozotocin; CE: chronic exercise; AE: acute exercise. N = 8.