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. 2012 Dec 13;7(12):e51524. doi: 10.1371/journal.pone.0051524

Figure 1. Effect of hypoxia and DOR activation on the cortex and body weight.

Figure 1

A, Cortex weight (n = 9). B, Ratio of cortex to body weight for each study group (n = 6–9). C: control; C+DOR: control+DOR agonist UFP-512; H: hypoxia; H+DOR: hypoxia+ DOR agonist UFP-512. *p<0.05, **p<0.01, ***p<0.001. Note that small, but significant, drops in cortex weight were found in both 1-day and 10-day hypoxic animals, and the cortex/body weight ratio increased with 5–10 day hypoxia. Also note that UFP-512 did not have a detectable affect on cortex weights, but preserved more of the cortex/body weight ratio.