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. 2012 Dec 13;7(12):e51524. doi: 10.1371/journal.pone.0051524

Figure 2. Relative miRNA expression levels of miR-29b, -324-3p and -347 in the cortex following 1, 5 or 10 days of hypoxia or UFP-512 treatment.

Figure 2

C: control; C+DOR: control+DOR agonist UFP-512; H: hypoxia; H+DOR: hypoxia+ DOR agonist UFP-512. *p<0.05, **p<0.01, ***p<0.001. Note that miRNA expression levels of miR-29b, -324-3p and -347 were suppressed in earlier, but not later days (10-day) of hypoxia. UFP-512 suppressed these miRNAs’ expression in a similar way. These results suggest these miRNAs respond to hypoxia and DOR activation in the early period, but not in the extended duration.