Table 5. Cox Proportional Hazard Models between Attrition and Predictor Variables: 0–12 and 13–24 months on ART.
Variable | 0–12 months | 13–24 months | ||||||
Univariate | Multivariate | Univariate | Multivariate | |||||
HR (95% C.I) | P-value | HR (95% C.I) | P-value | HR (95% C.I) | P-value | HR (95% C.I) | P-value | |
Age (years) | ||||||||
<15 | 1 | 1 | 1 | 1 | ||||
≥15 | 0.84(0.64–1.12) | 0.235 | 0.85(0.63–1.16) | 0.307 | 0.82 (0.61–1.11) | 0.197 | 0.91 (0.66–1.27) | 0.597 |
Gender | ||||||||
Female | 1 | 1 | 1 | 1 | ||||
Male | 1.12 (0.98–1.29) | 0.098 | 1.12(0.97–1.29) | 0.122 | 1.20 (1.03–1.40) | 0.017 | 1.18(1.01–1.37) | 0.038 |
Type of health facility | ||||||||
Secondary | 1 | 1 | 1 | 1 | ||||
Tertiary | 0.59 (0.51–0.68) | <0.001 | 0.61 (0.51–0.73) | <0.001 | 1.93 (1.66–2.25) | <0.001 | 2.21 (1.83–2.67) | <0.001 |
WHO clinical stage | ||||||||
Stage I | 1 | 1 | 1 | 1 | ||||
Stage II | 0.87 (0.68–1.11) | 0.260 | 1.02 (0.79–1.32) | 0.889 | 1.50 (1.20–1.87) | <0.001 | 1.32(1.05–1.66) | 0.016 |
Stage III | 1.29 (1.01–1.64) | 0.039 | 1.20(0.93–1.53) | 0.159 | 1.13 (0.90–1.43) | 0.285 | 1.30(1.03–1.66) | 0.030 |
Stage IV | 1.65 (1.14–2.39) | 0.008 | 1.53(1.05–2.23) | 0.028 | 1.77 (1.12–2.81) | 0.015 | 1.90(1.20–3.02) | 0.007 |
CD4 count | ||||||||
<200 | 1 | 1 | 1 | 1 | ||||
200–350 | 0.90 (0.76–1.07) | 0.235 | 0.96(0.81–1.15) | 0.672 | 0.95 (0.79–1.13) | 0.539 | 1.01(0.84–1.20) | 0.930 |
>350 | 0.98 (0.76–1.26) | 0.871 | 1.13(1.03–1.37) | 0.384 | 1.20 (0.94–1.52) | 0.148 | 1.27(0.98–1.65) | 0.070 |
Type of Regimen | ||||||||
AZT based | 1 | 1 | 1 | 1 | ||||
d4T based | 1.10 (0.96–1.27) | 0.161 | 1.19(1.03–1.37) | 0.019 | 1.04 (0.89–1.21) | 0.630 | 0.76 (0.63–0.91) | 0.002 |
TDF based | 4.72 (2.10–10.64) | <0.001 | 7.15(2.61–19.57) | <0.001 | 0.33 (0.10–1.01) | 0.053 | 0.30(0.10–0.93) | 0.038 |