Figure 5.
Sex differences in markers of inflammation and adiponectin expression in visceral adipose tissue in mice with steatosis induced by feeding a 30% fructose solution. (A) Representative photomicrographs of immunohistochemical staining of F4/80+ cells (630× with oil immersion) and (B) number of F4/80+ cells in visceral adipose tissue of male and female mice (n = 4–6 as histological material lacked). Expression levels of (C) mPGES1 (n = 5–6) and (D) adiponectin (n = 6) mRNA in visceral adipose tissue of mice. Expression of mRNA was determined by real time RT-PCR with β-actin as a reference gene in visceral fat. Data are shown as means ± SEM (n = 5–6) and are specified as -fold induction. C—water (control); F—30% fructose solution. *p < 0.05 compared with respective water fed control mice.