Figure 6.
Survival of transplanted iPS-derived pigmented RPE in albino Rpe65rd12/Rpe65rd12 mice. (A) Fundus photograph shows a patch of black pigmented iPS-RPE (arrowhead) behind the albino retinal 5 months after transplantation. No gross disruption of the host retina occurred. (B,C) Histology of host retina 5 months after transplantation. White arrowheads indicate mouse RPE (B). Human pigmented cells, indicated with black arrowheads, are adjacent to the host RPE (C). CH, choroid; PR, photoreceptor.