Table 3.
Diagnostic Characteristic |
ECG | NTBNP | cTnT | Score ≥ 1 | Score ≥ 2 | Score 3 |
---|---|---|---|---|---|---|
Sensitivity | 26% (16.8–31.8) |
55% (43.8–61.2) |
50% (41.6–59.1) |
76% (67.4–82.5) |
44% (33.8–51) |
9% (4.7–15) |
Specificity | 96% (95.4–97) |
72% (70.6–78) |
77% (75.5–78.9) |
55% (52.7–61.2) |
90% (88.8–93.1) |
99% (98.2–99.8) |
PPV | 27% (19–35.5) |
10% (9.3–14.6) |
11% (8.9–14.1) |
9% (7.9–11.6) |
21% (18.2–29.2) |
50% (30.6–73.2) |
NPV | 96% (94.7–96.4) |
97% (95.7–97.4) |
96% (95.5–97.2) |
98% (96.8–98.4) |
97% (95.7–97.2) |
95% (94.1–95.8) |
Positive LR | 6.3 (4.38–9.1) |
2.0 (1.95–2.77) |
2.2 (1.84–2.66) |
1.7 (1.66–2.06) |
4.6 (4.16–6.73) |
17.4 (8.5–42.1) |
Negative LR | 0.8 (0.72–0.87) |
0.6 (0.51–0.73) |
0.6 (0.54–0.76) |
0.4 (0.31–0.56) |
0.6 (0.54–0.73) |
0.9 (0.87–0.97) |
PPV = positive predictive value, NPV = negative predictive value, LR= likelihood ratio, NT-proBNP= Amino-terminal B-type natriuretic peptide, cTnT= highly sensitive cardiac troponin T.