Table 4.
Area under the curve values for individual and combined diagnostic test groups.
| Test Group | n | LVH Prevalence |
ECG | cTnT | NTBNP | ECG + cTnT |
ECG + NTBNP |
ECG + NTBNP + cTnT |
|---|---|---|---|---|---|---|---|---|
| Overall | 2478 | 5.4% | 0.760 (0.716–0.804) |
0.658 (0.611–0.705) |
0.657 (0.602–0.711) |
0.780* (0.738–0.822) |
0.796* (0.752–0.840) |
0.798*† (0.754–0.842) |
| Age < 50 | 1786 | 4.6% | 0.770 (0.716–0.824) |
0.649 (0.590–0.707) |
0.622 (0.551–0.693) |
0.785 (0.733–0.838) |
0.797 (0.744–0.851) |
0.798 (0.745–0.851) |
| Age >50 | 692 | 7.7% | 0.757 (0.683–0.832) |
0.650 (0.570–0.731) |
0.690 (0.605–0.774) |
0.784 (0.712–0.856) |
0.794* (0.719–0.870) |
0.801* (0.727–0.876) |
| Male | 1115 | 6.4% | 0.719 (0.657–0.781) |
0.697 (0.629–0.765) |
0.709 (0.636–0.782) |
0.761* (0.703–0.819) |
0.794* (0.735–0.853) |
0.795*‡ (0.736–0.854) |
| Female | 1363 | 4.7% | 0.792 (0.728–0.856) |
0.614 (0.554–0.674) |
0.630 (0.546–0.713) |
0.794 (0.730–0.858) |
0.802 (0.736–0.867) |
0.803 (0.738–0.869) |
| HTN no | 1788 | 2.0% | 0.782 (0.698–0.866) |
0.578 (0.496–0.660) |
0.509 (0.389–0.628) |
0.797 (0.714–0.880) |
0.790 (0.704–0.876) |
0.789 (0.703–0.876) |
| HTN yes | 690 | 14.3% | 0.733 (0.678–0.789) |
0.640 (0.581–0.698) |
0.680 (0.620–0.740) |
0.745*† (0.691–0.799) |
0.773*‡ (0.718–0.827) |
0.773*‡ (0.718–0.827) |
| Black | 1169 | 9.8% | 0.704 (0.653–0.756) |
0.642 (0.590–0.694) |
0.695 (0.639–0.751) |
0.730*† (0.681–0.780) |
0.762* (0.711–0.813) |
0.763* (0.712–0.813) |
| Other | 1309 | 1.6% | 0.744 (0.612–0.876) |
0.640 (0.520–0.762) |
0.581 (0.419–0.744) |
0.751 (0.617–0.884) |
0.763 (0.636–0.890) |
0.763 (0.636–0.891) |
| BMI | ||||||||
| <25 | 590 | 3.7% | 0.820 (0.744–0.897) |
0.626 (0.512–0.740) |
0.711 (0.564–0.858) |
0.852† (0.788–0.916) |
0.893*‡ (0.840–0.945) |
0.896* (0.841–0.951) |
| 25–30 | 807 | 5.3% | 0.765 (0.687–0.842) |
0.605 (0.521–0.690) |
0.611 (0.512–0.710) |
0.776 (0.699–0.851) |
0.782 (0.704–0.859) |
0.791* (0.715–0.867) |
| 30–35 | 562 | 6.2% | 0.748 (0.651–0.845) |
0.713 (0.623–0.803) |
0.671 (0.569–0.772) |
0.764 (0.667–0.860) |
0.787 (0.693–0.882) |
0.792* (0.697–0.886) |
| >35 | 519 | 6.7% | 0.765 (0.678–0.852) |
0.680 (0.588–0.773) |
0.693 (0.590–0.796) |
0.820* (0.739–0.900) |
0.796 (0.705–0.886) |
0.822* (0.740–0.905) |
*
p-value <0.05 vs ECG alone,
†
p-value <0.05 vs ECG+NTproBNP,
‡
p-value <0.05 vs ECG+hsTnT.
Parentheses indicate 95% confidence interval.