Table 1.
Number of micrometastases and macrometastases observed 30 days after injection of DHD/K12 cell line in BDIX rats
| Protocol | Metastases | Mean total number | Mean number in the right liver | Mean number in the left liver |
|---|---|---|---|---|
| Intraportal injection of 1 × 106 DHD/K12 | Micrometastases | 12 ± 2 (9–14) | 3 ± 1 (1–4) | 9 ± 1 (7–10) |
| Macrometastases | 0 | 0 | 0 | |
| Intraportal injection of 2 × 106 DHD/K12 | Micrometastases | 17 ± 2 (15–20) | 5 ± 1 (4–6) | 12 ± 1 (11–14) |
| Macrometastases | 0 | 0 | 0 | |
| Intraportal injection of 3 × 106 DHD/K12 | Micrometastases | 22 ± 2 (21–25) | 7 ± 1 (6–9) | 15 ± 1 (14–16) |
| Macrometastases | 0 | 0 | 0 | |
| Intraportal injection of 1 × 106 and direct injection of 0.5 × 106 DHD/K12 | Micrometastases | 11 ± 1 (9–12) | 3 ± 1 (3–5) | 7 ± 1 (6–9) |
| Macrometastases | 1 | 0 | 1 | |
| Intraportal injection of 1 × 106 and direct injection of 0.5 × 106 DHD/K12 | Micrometastases | 12 ± 3 (9–15) | 4 ± 0 (4–5) | 8 ± 3 (5–11) |
| Macrometastases | 1 | 0 | 1 | |
| Intraportal injection of 1 × 106 and direct injection of 0.5 × 106 DHD/K12 | Micrometastases | 10 ± 1 (10–12) | 4 ± 1 (3–5) | 6 ± 1 (5–7) |
| Macrometastases | 1 | 0 | 1 |