Whole-brain fMRI analysis of reality-monitoring activity reveals signal increase within: (a) the medial prefrontal cortex (mPFC) in 15 healthy comparison (HC) subjects, (b) the posterior cingulate cortex, rather than the mPFC, in patients with schizophrenia (SZ) prior to computerized cognitive training, and (c) the mPFC in only the group of SZ patients who completed 80 h of active computerized cognitive training (SZ-AT), which is similar to the neural activation patterns observed in the HC sample (see Subramaniam et al, 2012).