Scattergrams and correlation analysis of Pimonidazole microscopy, Pimo, vs.
64Cu-ATSM autoradiography, Autorad, in four representative tumors. Figures (a) and (b) show Pimo vs. early Autorad at 1 h post-injection of 64Cu-ATSM. Figures (c) and (d) show Pimo vs. late Autorad at 18 h. The central 99% of pixel values from scattergrams (a.1), (b.1), (c.1), and (d.1) were binned into deciles for analysis of spatial correlation between the Pimo vs. Autorad microdistributions. This correlation analysis is shown in the plots correspondingly labeled (a.2), (b.2), (c.2), and (d.2).