Table 3.
The association of clinical characteristics with Hint1 methylation status
| Tumor tissues |
|||
|---|---|---|---|
| Variable | Non-methylated | Methylated | P |
| Adjacent non-tumor tissues | |||
| Non-methylated | 15 | 9 | 0.01 |
| Methylated | 3 | 12 | |
| Missing | 0 | 1 | |
| Hint 1 protein expression | |||
| No | 3 | 14 | 0.003 |
| Yes | 15 | 8 | |
| Grade | |||
| I orII | 11 | 8 | 0.49 |
| IIIor IV | 2 | 8 | |
| Missing | 5 | 6 | |
| Liver cirrhosis | |||
| No | 9 | 9 | 0.71 |
| Yes | 6 | 7 | |
| Missing | 3 | 6 | |
| HBsAg | |||
| Negative | 3 | 2 | 0.44 |
| Positive | 12 | 15 | |
| Missing | 3 | 5 | |
| Aflatoxin B1-adducts | |||
| Low | 11 | 7 | 0.07 |
| Medium | 3 | 11 | |
| High | 4 | 4 | |
| PAH-adducts | |||
| Low | 9 | 13 | 0.49 |
| Medium | 4 | 7 | |
| High | 4 | 2 | |
| Missing | 1 | 0 | |
| p16 methylation | |||
| No | 10 | 5 | 0.035 |
| Yes | 8 | 17 | |