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. Author manuscript; available in PMC: 2012 Dec 14.
Published in final edited form as: Biochem Biophys Res Commun. 2012 Apr 4;421(2):208–213. doi: 10.1016/j.bbrc.2012.03.136

Figure 2.

Figure 2

Global arrangement of SefDdscA molecules within crystals grown in 0% and 100% D2O. (A) Domain-swapped dimer of SefDdscA in 0% D2O. The single molecule of the asymmetric unit is coloured yellow whilst its symmetry mate is coloured olive. The dimer face is composed of a hydrophobic surface and solely backbone hydrogen bonding within the A2-G′-G-A2′ sheets. (B) Crystal packing in the 0% and 100% D2O crystal forms. Top panel: SefDdscA molecules (green) form ‘rod-like’ structures and the unit cells are viewed down the crystallographic c-axis. The spacegroup C2221 (0% D2O: red box) is a subgroup of P6522 (orange box) and is very similar to the P212121 (100% D2O: red box) packing. Bottom panel: SefDdscA domain-swapped dimers (red, blue and green) viewed parallel to half the unit cell c-axis. The asymmetric units are represented as dashed boxes.