Table 2.

Mean (± SEM) index of curvature data for all six FI-240 sec experiments

		Vehicle	5.0 mg/kg	10.0 mg/kg	20.0 mg/kg	40.0 mg/kg
Caffeinea	Mean	0.306	0.277	0.230	0.249	0.132
	SEM	0.042	0.023	0.020	0.030	0.030
		Vehicle	5.0 mg/kg	10.0 mg/kg	20.0 mg/kg	40.0 mg/kg
Theophylline	Mean	0.258	0.327	0.257	0.145	0.185
	SEM	0.060	0.041	0.036	0.034	0.052
		Vehicle	0.5 mg/kg	1.0 mg/kg	2.0 mg/kg	4.0 mg/kg
MSX-3	Mean	0.370	0.259	0.307	0.301	0.387
	SEM	0.045	0.050	0.043	0.040	0.047
		Vehicle	0.125 mg/kg	0.25 mg/kg	0.5 mg/kg	1.0 mg/kg
Istradefylline	Mean	0.414	0.260	0.311	0.321	0.289
	SEM	0.041	0.047	0.018	0.026	0.053
		Vehicle	0.1875 mg/kg	0.375 mg/kg	0.75 mg/kg	1.5 mg/kg
DPCPX	Mean	0.31	0.33	0.32	0.36	0.30
	SEM	0.06	0.03	0.03	0.03	0.03
		Vehicle	1.5 mg/kg	3.0 mg/kg	6.0 mg/kg	12.0 mg/kg
CPT	Mean	0.438	0.265	0.416	0.298	0.282
	SEM	0.055	0.044	0.044	0.070	0.054

^asignificant overall effect; 40.0 mg/kg caffeine significantly differed from vehicle.