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. 2012 Jun 13;21(1):102–108. doi: 10.1038/ejhg.2012.98

Table 3. Age of the hexanucleotide repeat expansion mutation.

Growth rate (%) Generations Years
8.5 157 (134–196) 3900 (2700–5900)
5 251 (220–287) 6300 (4400–8600)
2.5 479 (419–550) 12 000 (8400–16 500)

Estimates of the age of the HREM for a range of per-generation human population, growth estimates are given in ‘generations' (with 2.5 and 97.5% quantiles) and ‘years', estimated with a 25-generation interval (with 20- and 30-year intervals).