Table 3. Age of the hexanucleotide repeat expansion mutation.
Growth rate (%) | Generations | Years |
---|---|---|
8.5 | 157 (134–196) | 3900 (2700–5900) |
5 | 251 (220–287) | 6300 (4400–8600) |
2.5 | 479 (419–550) | 12 000 (8400–16 500) |
Estimates of the age of the HREM for a range of per-generation human population, growth estimates are given in ‘generations' (with 2.5 and 97.5% quantiles) and ‘years', estimated with a 25-generation interval (with 20- and 30-year intervals).