TABLE 1.

Equilibrium dissociation binding constants of RIG-I constructs with 14 dsRNA

	Full-length RIG-I Kd	RIG-I (ΔCARDs) Kd	HD Kd	CTD Kd
	nm	nm	nm	nm
5′-OH 14 dsRNA	20 ± 3	3.6 ± 0.9	1830 ± 250	5900 ± 750
5′-ppp 14 dsRNA	0.159 ± 0.020	0.041 ± 0.002	760 ± 20	0.500 ± 0.060