Figure 2.  .

Examples of ocular mutants identified in the screen. uta¹ (A') and uta³ mutants (B') display colobomas at 3 dpf when compared with phenotypically wild-type siblings ([A, B], respectively). Arrows in (A') and (B') point to the open choroid fissure in the mutants. uta⁵ mutants (C') lack photoreceptors in the central retina at 7 dpf when compared with phenotypically wild-type siblings (C). Photoreceptors are detected at the peripheral retina, adjacent to the ciliary marginal zones in mutant embryos (arrows in [C']). uta¹⁹ mutants (D') possess visible cataracts at 6 dpf when compared with phenotypically wild-type siblings (D). Arrow in (D') highlights cataract in mutant lens. uta¹⁶ mutants (E') possess severe defects in lens morphology at 7 dpf when compared with phenotypically wild-type siblings (E). Arrows in (E') highlight mutant lenses.