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TCC biotransformation by human keratinocytes. Parallel SIK cultures pretreated one day ± 10 nM TCDD as indicated were then treated for 20 hr with 2 μM TCC. The metabolite levels detected were normalized to protein concentration (3.6 ± 0.4 mg/ml without TCDD; 4.1 ± 0.3 mg/ml after TCDD treatment). DHC, 3,4-dichloro-4’-hydroxy-carbanilide. Each experiment was conducted in triplicate, and values are presented as means ± SD.
