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. Author manuscript; available in PMC: 2012 Dec 14.
Published in final edited form as: Int J Biochem Cell Biol. 2009 Apr 2;41(10):1957–1971. doi: 10.1016/j.biocel.2009.03.011

Figure 5. Mitochondrial Ca2+ cycling in ventricular myocytes.

Figure 5

Schematic of local Ca2+ cycling in ventricular cardiac myocytes: sarcolemmal, SR, and mitochondrial Ca2+ cycling. This schematic is a conceptual representation of the location of structures involved in the local interplay of IMFM, SR, and sarcolemmal Ca2+ cycling. ADP, adenosine diphosphate; ANT, adenine nucleotide translocase; ATP, adenosine trisphosphate; junctional sarcoplasmic reticulum, MCU, electrogenic mitochondrial Ca2+ uniporter; mNCX, Na+/Ca2+ exchanger; NHE, Na+/H+ exchanger; nSR, network SR; PTP, permeability transition pore; RaM, rapid mode of Ca2+ uptake; TT, Transverse tubule; VDAC, voltage-dependent anion channel.