Table 1.
Baseline demographics and clinical characteristics of subjects
| Demographics | ||
|
| ||
| Age (years) | 72 ± 10 | |
| Gender (# female/male) | 13/1 | |
| BMI (kg/m2) | 35.5 ± 7.9 | |
|
| ||
| Baseline characteristics | n (%) | Comments |
|
| ||
| Hypertension | 14 (100%) | No known secondary causes |
| Coronary artery disease | 5 (36%) | 1 with prior CABG, 1 with prior PCI |
| Diabetes mellitus | 6 (43%) | All type II; Hgb A1c 6.8 ± 0.8% |
| Chronic kidney disease | 14 (100%) | eGFR 60 ± 17 ml/min/1.73 m2 |
| Stage II (eGFR 60–90) | 6 (43%) | |
| Stage III (eGFR < 60) | 8 (57%) | |
| Anemia | 6 (43%) | Hematocrit 38 ± 5% |
| NYHA class III | 12 (86%) | |
| Prior heart failure hospitalization | 10 (71%) | |
| On chronic loop diuretic therapy | 11 (79%) | |
| On 3 antihypertensives * | 10 (71%) | |
Abbreviations: BMI: body mass index; CABG: coronary artery bypass grafting; NYHA: New York Heart Association; eGFR: estimated glomerular filtration rate per Modification of Diet in Renal Disease; PCI: percutaneous coronary intervention