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. Author manuscript; available in PMC: 2012 Dec 14.
Published in final edited form as: Circulation. 2005 Sep 12;112(12):1687–1691. doi: 10.1161/CIRCULATIONAHA.105.553438

TABLE 2.

Annual Unadjusted Incidence Rates of Thromboembolism Among Men and Women With Atrial Fibrillation Not Taking Warfarin Stratified by Known Risk Factors for Stroke and CHADS2 Score*

Risk Factor Annual Thromboembolism Rate (95% CI)
Women Men
Age ≥75 y 5.0 (4.3–5.7) 2.8 (2.3–3.4)
Prior ischemic stroke 9.7 (7.0–13.6) 7.3 (5.2–10.3)
Diagnosed hypertension 4.0 (3.4–4.7) 2.4 (2.0–3.0)
Diagnosed congestive heart failure 5.7 (4.7–6.9) 2.5 (1.9–3.2)
Diagnosed coronary artery disease 4.7 (3.8–6.0) 2.4 (1.9–3.1)
Diabetes mellitus 5.0 (3.7–6.6) 3.1 (2.3–4.2)
CHADS2 score
 0 0.6 (0.2–1.2) 0.5 (0.3–0.9)
 1 1.8 (1.3–2.4) 1.2 (0.9–1.7)
 2 4.4 (3.6–5.4) 1.9 (1.4–2.6)
 3 6.1 (4.8–7.8) 3.9 (2.8–5.3)
 4 9.1 (6.2–13.3) 6.5 (4.2–10.0)
 5 7.7 (3.6–16.5) 2.6 (0.8–8.1)
 6 11.4 (2.5–51.9) 16.2 (7.4–35.6)
*

CHADS2 score calculated by assigning 2 points to prior stroke or transient ischemic attack and 1 point to any of the following risk factors: congestive heart failure, hypertension, age ≥75 years, and diabetes mellitus.