Table 1.
SEREX-defined genes identified by autologous screening of C-164 cDNA library
| Antigen | No. of clones | Identity/similarities |
DNA microarray (fold change)1 |
||
|---|---|---|---|---|---|
| C-164 | C-1 | C-29 | |||
| OY-CO-1 |
1 |
Lectin, galactoside-binding, soluble, 3 binding protein (LGALS3BP) |
0.72 |
0.60 |
0.46 |
| OY-CO-2 |
1 |
Rho GTPase-activating protein 18(ARHGAP18) |
4.57 |
1.44 |
1.50 |
| OY-CO-3 |
10 |
Dihydrolipoamide dehydrogenase (DLD) |
1.27 |
0.55 |
0.30 |
| OY-CO-4 |
1 |
Adenomatous polyposis coli (APC), transcript variant 3 |
3.61 |
0.74 |
3.22 |
| OY-CO-5 |
1 |
MRE11 meiotic recombination 11 homolog A (MRE11A), transcript variant 1 |
2.66 |
9.02 |
3.72 |
| OY-CO-6 |
1 |
Heat shock protein 90 kDa beta (Grp94), member 1 (HSP90B1) |
1.02 |
2.75 |
1.25 |
| OY-CO-7 |
1 |
Transcription elongation factor B (SII), polypeptide 2 (18 kDa, elongin B) (TCEB2), transcript variant 1 |
1.52 |
2.74 |
1.48 |
| OY-CO-8 |
1 |
Wilms tumor 1-associated protein (WTAP), transcript variant 2 |
1.06 |
0.35 |
0.42 |
| OY-CO-9 |
1 |
Ribosomal protein L35a (RPL35A) |
1.77 |
1.95 |
2.31 |
| OY-CO-10 |
1 |
Polyglutamine-binding protein 1 (PQBP1), transcript variant 7 |
1.26 |
1.27 |
1.30 |
| OY-CO-11 |
2 |
PRP38 pre-mRNA processing factor 38 (yeast) domain containing B (PRPF38B), transcript variant 1 |
3.03 |
2.88 |
2.51 |
| OY-CO-12 |
2 |
Coatomer protein complex, subunit alpha (COPA), transcript variant 2 |
1.26 |
0.73 |
0.75 |
| OY-CO-13 |
1 |
Keratin 18 (KRT18), transcript variant 1 |
1.46 |
1.24 |
0.66 |
| OY-CO-14 |
1 |
No strong homology, retrotransposon MSTP055 mRNA |
- |
- |
- |
| OY-CO-15 |
1 |
Ribosomal protein L13 (RPL13), transcript variant 2 |
0.92 |
0.84 |
1.67 |
| OY-CO-16 |
1 |
Partial mRNA for KLEIP (kelch-like ECT2 interacting protein), (KLHLX gene) |
- |
- |
- |
| OY-CO-17 |
2 |
BTB (POZ) domain containing 2 (BTBD2) |
0.79 |
0.84 |
0.83 |
| OY-CO-18 |
1 |
Nuclear receptor interacting protein 1 (NRIP1) |
0.81 |
0.87 |
0.92 |
| OY-CO-19 |
1 |
Ribosomal protein L8 (RPL8), transcript variant 2 |
1.01 |
2.63 |
1.69 |
| OY-CO-20 |
2 |
Glutamine-fructose-6-phosphate transaminase 1 (GFPT1) |
2.92 |
1.00 |
0.59 |
| OY-CO-21 | 1 | WD repeat, sterile alpha motif and U-box domain containing 1 (WDSUB1), transcript variant 3 | 1.69 | 1.19 | 0.76 |
1Gene expressions in 3 colon cancer tissues were compared with normal colon tissues by cDNA microarray analysis.