Table 10.
Effect of DAS-77 on serum electrolytes in the reversibility study
|
Treatment |
Dose (mg/kg) |
Reversibility study |
||||
|---|---|---|---|---|---|---|
|
Na+ (mmol/L) |
K+(mmol/L) |
Cl− (mmol/L) |
HCO3−(mmol/L) | Ca2+(mg/dl) | ||
|
Distilled water |
(10 ml/kg) |
154.90 ± 1.29 |
5.19 ± 0.17 |
104.50 ± 0.93 |
11.38 ± 0.68 |
1.18 ± 0.05 |
|
DAS-77 |
80 |
154.80 ± 0.64 |
4.99 ± 0.17 |
106.70 ± 0.71 |
12.33 ± 0.88 |
1.12 ± 0.05 |
|
DAS-77 |
400 |
153.30 ± 0.80 |
5.09 ± 0.15 |
105.80 ± 1.07 |
11.63 ± 0.60 |
1.15 ± 0.04 |
| DAS-77 | 2000 | 158.00 ± 1.07 | 5.10 ± 0.15 | 108.20 ± 1.17 | 11.83 ± 0.60 | 1.08 ± 0.05 |
Values are mean ± S.E.M. (n = 10). p > 0.05 vs. distilled water (One-way ANOVA followed by Dunnett’s posttest).