Table 2.
|
|
Main study |
Reversibility study |
||||
---|---|---|---|---|---|---|---|
Treatment | Dose (mg/kg) | Sperm motility (%) | Sperm count (million/ml) | Abnormality (%) | Sperm motility (%) | Sperm counted (million/ml) | Abnormality (%) |
Distilled water |
(10 ml/kg) |
85.00 ± 6.00 |
31.14 ± 2.50 |
5.14 ± 1.10 |
81.60 ± 7.17 |
25.80 ± 4.28 |
7.20 ± 1.72 |
DAS-77 |
80 |
73.43 ± 12.61 |
25.57 ± 4.07 |
8.86 ± 2.42 |
72.33 ± 9.30 |
24.67 ± 3.53 |
8.33 ± 2.01 |
DAS-77 |
400 |
87.29 ± 12.05 |
33.00 ± 3.52 |
4.14 ± 1.44 |
70.80 ± 9.07 |
23.00 ± 2.54 |
7.40 ± 1.50 |
DAS-77 | 2000 | 42.71 ± 10.33* | 14.71 ± 3.00** | 12.43 ± 2.26* | 74.25 ± 13.56 | 25.50 ± 5.52 | 5.50 ± 1.71 |
Values are mean ± S.E.M (n = 7, main study; n = 5, reversibility study). *p < 0.05, **p < 0.01 vs. distilled water (One-way ANOVA followed by Dunnett’s posttest).