Table 4.

Effect of DAS-77 on weight of vital organs (per 100 g body weight) in the reversibility study

Treatment	Dose (mg/kg)	Reversibility study
		Liver	Kidney	Lungs	Heart	Testes	Spleen	Pancreas	Brain	Ovaries
Distilled water	(10 ml/kg)	2.60 ± 0.11	0.57 ± 0.01	0.73 ± 0.06	0.36 ± 0.02	1.39 ± 0.13	0.29 ± 0.01	0.25 ± 0.03	0.78 ± 0.03	0.12 ± 0.00
DAS-77	80	2.53 ± 0.12	0.55 ± 0.03	0.68 ± 0.03	0.35 ± 0.02	1.21 ± 0.05	0.25 ± 0.01	0.24 ± 0.02	0.82 ± 0.04	0.10 ± 0.01
DAS-77	400	2.74 ± 0.12	0.62 ± 0.01	0.88 ± 0.0*	0.42 ± 0.03	0.95 ± 0.27	0.25 ± 0.01	0.26 ± 0.02	0.71 ± 0.04	0.12 ± 0.01
DAS-77	2000	2.79 ± 0.10	0.63 ± 0.05	0.83 ± 0.02	0.38 ± 0.03	1.35 ± 0.28	0.27 ± 0.02	0.34 ± 0.02	0.82 ± 0.04	0.14 ± 0.01

Values are mean ± S.E.M (n = 10). ^*p < 0.05 vs. distilled water (One-way ANOVA followed by Dunnett’s posttest).