Table 5. Associations between high BMI and large WC of 8-and-12-year-old children and total and HDL cholesterol concentrations and total-to HDL cholesterol ratio in 12-year-old girls and boys compared with girls and boys with a normal BMI or WC at both ages (normal-normal).
Girls n = 505 | Boys n = 489 | ||||||||||||
Totalcholesterol | HDLcholesterol | Total-to-HDLcholesterol ratio | Totalcholesterol | HDLcholesterol | Total-to-HDLcholesterol ratio | ||||||||
β | 95% CI | β | 95% CI | B | 95% CI | β | 95% CI | β | 95% CI | β | 95% CI | ||
BMI 90th centile | |||||||||||||
B | |||||||||||||
High-Normal | 0.25 | (−0.07, 0.57) | −0.04 | (−0.19, 0.10) | 0.29 | (−0.09, 0.68) | 0.13 | (−0.18, 0.45) | 0.08 | (−0.07, 0.22) | 0.01 | (−0.38, 0.40) | |
Normal-High | 0.26 | (−0.05, 0.57) | −0.09 | (−0.24, 0.05) | 0.47 | (0.10, 0.84) | 0.23 | (−0.06, 0.52) | −0.16 | (−0.29, −0.03) | 0.69 | (0.33, 1.04) | |
High-High | −0.08 | (−0.30, 0.14) | −0.19 | (−0.29, −0.09) | 0.48 | (0.22, 0.75) | 0.53 | (0.30, 0.77) | −0.19 | (−0.30, −0.08) | 0.98 | (0.69, 1.27) | |
C | |||||||||||||
High-Normal | 0.06 | (−0.30, 0.41) | −0.04 | (−0.20, 0.13) | 0.10 | (−0.32, 0.53) | −0.04 | (−0.36, 0.29) | 0.13 | (−0.02, 0.29) | −0.29 | (−0.69, 0.11) | |
Normal-High | −0.04 | (−0.41, 0.33) | −0.05 | (−0.21, 0.12) | 0.07 | (−0.37, 0.50) | −0.04 | (−0.36, 0.27) | −0.13 | (−0.28, 0.02) | 0.38 | (−0.00, 0.76) | |
High-High | −0.40 | (−0.75, 0.05) | −0.13 | (−0.29, 0.03) | −0.00 | (−0.41, 0.41) | 0.03 | (−0.38, 0.32) | −0.07 | (−0.24, 0.10) | 0.11 | (−0.32, 0.54) | |
WC 90th centile | |||||||||||||
B | |||||||||||||
High-Normal | 0.17 | (−0.08, 0.40) | −0.03 | (−0.14, 0.08) | 0.21 | (−0.07, 0.50) | 0.09 | (−0.19, 0.37) | −0.07 | (−0.21, 0.06) | 0.28 | (−0.06, 0.62) | |
Normal-High | 0.37 | (0.10, 0.62) | −0.11 | (−0.23, 0.02) | 0.62 | (0.30, 0.93) | 0.58 | (0.30, 0.86) | −0.13 | (−0.26, 0.00) | 0.84 | (0.49, 1.18) | |
High-High | 0.06 | (−0.19, 0.29) | −0.22 | (−0.33, −0.10) | 0.70 | (0.40, 0.99) | 0.71 | (0.47, 0.95) | −0.20 | (−0.32, −0.09) | 1.22 | (0.92, 1.52) | |
C | |||||||||||||
High-Normal | 0.30 | (−0.00, 0.61) | 0.03 | (−0.11, 0.17) | 0.19 | (−0.17, 0.55) | 0.10 | (−0.19, 0.40) | −0.10 | (−0.24, 0.04) | 0.34 | (−0.02, 0.70) | |
Normal-High | 0.45 | (0.13, 0.78) | −0.07 | (−0.21, 0.08) | 0.59 | (0.21, 0.97) | 0.60 | (0.29, 0.92) | −0.07 | (−0.22, 0.08) | 0.68 | (0.30, 1.07) | |
High-High | 0.37 | (−0.01, 0.74) | −0.12 | (−0.29, 0.06) | 0.69 | (0.24, 1.13) | 0.74 | (0.36, 1.11) | −0.09 | (−0.34, 0.01) | 1.16 | (0.70, 1.61) |
BMI: body mass index, WC, waist circumference, HDL: high density lipoprotein.
Model B: adjusted for pre-pregnancy maternal overweight, puberty development scale, age at the time of the measurements, height.
Model C: additionally adjusted for WC (in BMI analyses) and BMI (in WC analyses).