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. 2012 Dec 14;7(12):e51801. doi: 10.1371/journal.pone.0051801

Table 5. Associations between high BMI and large WC of 8-and-12-year-old children and total and HDL cholesterol concentrations and total-to HDL cholesterol ratio in 12-year-old girls and boys compared with girls and boys with a normal BMI or WC at both ages (normal-normal).

Girls n = 505 Boys n = 489
Totalcholesterol HDLcholesterol Total-to-HDLcholesterol ratio Totalcholesterol HDLcholesterol Total-to-HDLcholesterol ratio
β 95% CI β 95% CI B 95% CI β 95% CI β 95% CI β 95% CI
BMI 90th centile
B
High-Normal 0.25 (−0.07, 0.57) −0.04 (−0.19, 0.10) 0.29 (−0.09, 0.68) 0.13 (−0.18, 0.45) 0.08 (−0.07, 0.22) 0.01 (−0.38, 0.40)
Normal-High 0.26 (−0.05, 0.57) −0.09 (−0.24, 0.05) 0.47 (0.10, 0.84) 0.23 (−0.06, 0.52) 0.16 (0.29,0.03) 0.69 (0.33, 1.04)
High-High −0.08 (−0.30, 0.14) 0.19 (0.29,0.09) 0.48 (0.22, 0.75) 0.53 (0.30, 0.77) 0.19 (0.30,0.08) 0.98 (0.69, 1.27)
C
High-Normal 0.06 (−0.30, 0.41) −0.04 (−0.20, 0.13) 0.10 (−0.32, 0.53) −0.04 (−0.36, 0.29) 0.13 (−0.02, 0.29) −0.29 (−0.69, 0.11)
Normal-High −0.04 (−0.41, 0.33) −0.05 (−0.21, 0.12) 0.07 (−0.37, 0.50) −0.04 (−0.36, 0.27) −0.13 (−0.28, 0.02) 0.38 (−0.00, 0.76)
High-High −0.40 (−0.75, 0.05) −0.13 (−0.29, 0.03) −0.00 (−0.41, 0.41) 0.03 (−0.38, 0.32) −0.07 (−0.24, 0.10) 0.11 (−0.32, 0.54)
WC 90th centile
B
High-Normal 0.17 (−0.08, 0.40) −0.03 (−0.14, 0.08) 0.21 (−0.07, 0.50) 0.09 (−0.19, 0.37) −0.07 (−0.21, 0.06) 0.28 (−0.06, 0.62)
Normal-High 0.37 (0.10, 0.62) −0.11 (−0.23, 0.02) 0.62 (0.30, 0.93) 0.58 (0.30, 0.86) 0.13 (0.26, 0.00) 0.84 (0.49, 1.18)
High-High 0.06 (−0.19, 0.29) 0.22 (0.33,0.10) 0.70 (0.40, 0.99) 0.71 (0.47, 0.95) 0.20 (0.32,0.09) 1.22 (0.92, 1.52)
C
High-Normal 0.30 (−0.00, 0.61) 0.03 (−0.11, 0.17) 0.19 (−0.17, 0.55) 0.10 (−0.19, 0.40) −0.10 (−0.24, 0.04) 0.34 (−0.02, 0.70)
Normal-High 0.45 (0.13, 0.78) −0.07 (−0.21, 0.08) 0.59 (0.21, 0.97) 0.60 (0.29, 0.92) −0.07 (−0.22, 0.08) 0.68 (0.30, 1.07)
High-High 0.37 (−0.01, 0.74) −0.12 (−0.29, 0.06) 0.69 (0.24, 1.13) 0.74 (0.36, 1.11) −0.09 (−0.34, 0.01) 1.16 (0.70, 1.61)

BMI: body mass index, WC, waist circumference, HDL: high density lipoprotein.

Model B: adjusted for pre-pregnancy maternal overweight, puberty development scale, age at the time of the measurements, height.

Model C: additionally adjusted for WC (in BMI analyses) and BMI (in WC analyses).