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. 2012 Dec 14;7(12):e52002. doi: 10.1371/journal.pone.0052002

Figure 2. Immunohistochemical characteristics of RV in BMD compared to DMRV and sIBM.

Figure 2

Representative transverse serial sections of biopsied skeletal muscles from BMD with RV (left column), DMRV (center column) and sIBM (right column) patients. A–C: mGT staining similarly highlights the fibers with RVs (arrowheads) in all patients. D–F: LAMP-1 (red) co-stained with caveolin-3 (green), G–I: LC3, J–L: APP, M–O: Aβ1-42, P–R: polyUb proteins, and S–U: p62. Immunofluorescent signals are observed around RVs (arrowhead). Scale bar: 25 µm.