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. 2012 Dec 14;7(12):e52268. doi: 10.1371/journal.pone.0052268

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© 2012 Leclercq, Cordaux

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) Sequence spanning from positions −25 to +10 relative to full-length Kl.pn.I5 copy insertion sites are displayed and compared to predicted EBS. Identical bases and those which fit the Watson-Crick (stars) or the Wobble (plus) base-pairing with EBS motifs were used to construct the consensus homing site. (B) Regions surrounding Di.ze.I1 and So.gl.I1 full-length copies are displayed and compared to predicted EBS1 and EBS3. Most represented nucleotides at a given position and which fit the Watson-Crick (stars) or the Wobble (plus) base-pairing with EBS motifs were used to construct the consensus homing site. Stem-loops belonging to Rho-independent transcription terminators inferred by ARNold [58] are colored in blue (stems) and red (loops). Underlined sequences are stem-loops not detected by ARNold. (C) Weblogo diagram of the −25 to +10 region surrounding the 26 full-length c-Ha.de.I1 copies belonging to subgroup 1. Bases which show relative conservation were used to construct the consensus homing site.