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. 2012 Dec 14;7(12):e48851. doi: 10.1371/journal.pone.0048851

Table 1. Baseline characteristics.

Total1 SAVR1 TAVI1
N = 42 N = 13 N = 29 Sig.2
EuroSCORE 21 (12; 35) 18 (12; 28) 24 (12; 37) 0.025 *
EuroSCORE II (2011) 4.21 (1.84; 9.34) 3.81 (1.09; 7.35) 4.26 (1.85; 10.20) 0.295
Age (years) 82 (75; 89) 83 (76; 89) 82 (70; 89) 0.870
Gender (male) 13 (31.0%) 5 (38.5%) 8 (27.6%) 0.485
Creatinine clearance 3 (mL/min) 49.9 (29.7; 85.3) 56.8 (34.6; 85.3) 45.8 (26.9; 87.1) 0.153
Extracardiac arteriopathy 10 (23.8%) 4 (30.8%) 6 (20.7%) NS
Poor mobility 3 (7.1%) 1 (7.7%) 2 (6.9%) NS
Previous cardiac surgery 1 (2.4%) 0 (0.0%) 1 (3.4%) NS
Chronic lung disease 6 (14.3%) 1 (7.7%) 5 (17.2%) NS
Diabetes mellitus on insulin 4 (9.5%) 1 (7.7%) 3 (10.3%) NS
BMI (kg/m2) 27.6 (20.8; 34.4) 28.7 (20.6; 38.9) 27.4 (20.8; 33.8) 0.248
History of TIA/stroke 7 (16.7%) 3 (23.1%) 4 (13.8%) NS
Smoking 4 (9.5%) 0 (0.0%) 4 (13.8%) 0.076
NYHA II 6 (14.3%) 3 (23.1%) 3 (10.3%) 0.102
NYHA III 26 (61.9%) 8 (61.5%) 18 (62.1%)
NYHA IV 10 (23.8%) 2 (15.4%) 8 (27.6%)
EF LV (%) 57 (35; 75) 59 (51; 80) 57 (35; 72) 0.383
PA systolic 0–30 mmHg 14 (33.3%) 7 (53.8%) 7 (24.1%) 0.055
PA systolic 31–55 mmHg 16 (38.1%) 5 (38.5%) 11 (37.9%)
PA systolic >55 mmHg 12 (28.6%) 1 (7.7%) 11 (37.9%)
Echocardiography
Peak gradient (mmHg) 83 (57; 131) 96 (57; 132) 80 (54; 117) 0.264
Mean gradient (mmHg) 50 (33; 80) 57 (35; 80) 50 (32; 71) 0.119
AVA (cm2) 0.60 (0.40; 0.96) 0.60 (0.45; 0.97) 0.57 (0.39; 0.96) 0.270
AVA index 0.34 (0.20; 0.50) 0.40 (0.20; 0.52) 0.30 (0.20; 0.45) 0.070
Ejection fraction (%) 57 (35; 75) 59 (51; 80) 57 (35; 72) 0.383
LV diastolic diameter (mm) 46 (39; 54) 46 (39; 55) 47 (37; 54) 0.785
LV systolic diameter (mm) 32 (23; 42) 32 (23; 39) 32 (23; 45) 0.754
1

Categorical parameters are described by absolute number and percentage of patients in given category; continuous variables are described by median (5th; 95th percentile).

2

Overall statistical significance of differences among groups is based on Mann-Whitney test for continuous variables and ML chi-square test for categorical variables,

3

Creatinine clearance was estimated according to MDRD formula;

*

statistically significant.

BMI – Body mass index, TIA – Transitory ischemic attack, EF LV – Ejection fraction of left ventricle, PA systolic – Pulmonary artery systolic pressure, AVA – Aortic valve area.