Table 5. ROC analysis for prediction of endpoints in patients treated with SAVR and TAVI.

	1-year mortality		Combined safety endpoint at 30 days		Combined efficacy endpoint 31–365 days		Combined endpoint 0–356 days
	N = 6 (14.3%)		N = 8 (19.0%)		N = 8 (19.5%)		N = 15 (35.7%)
	Sig.	AUC (95% CI)	Sig.	AUC (95% CI)	Sig.	AUC (95% CI)	Sig.	AUC (95% CI)
EuroSCORE	0.014*	0.817 (0.654; 0.980)	0.120	0.678 (0.491; 0.866)	0.490	0.580 (0.321; 0.838)	0.203	0.620 (0.440; 0.800)
EuroSCORE II	0.289	0.637 (0.423; 0.850)	0.066	0.711 (0.507; 0.916)	0.162	0.661 (0.485; 0.837)	0.027*	0.709 (0.550; 0.867)
BNP	0.376	0.614(0.343;0.885)	0.844	0.523(0.332;0.714)	0.437	0.590(0.353;0.827)	0.432	0.574(0.394;0.755)
NTproBNP	0.590	0.569(0.327;0.812)	0.848	0.522(0.327;0.717)	0.469	0.583(0.366;0.800)	0.520	0.560(0.380;0.741)
Creatinine clearance	0.719	0.546 (0.332; 0.761)	0.063	0.713 (0.562; 0.864)	0.717	0.542 (0.326; 0.757)	0.131	0.642 (0.472; 0.812)
Cystatin C	0.685	0.552 (0.350; 0.755)	0.300	0.619 (0.417; 0.821)	0.839	0.477 (0.289; 0.664)	0.617	0.547 (0.373; 0.722)
ADMA	0.398	0.609 (0.418; 0.799)	0.923	0.489 (0.227; 0.751)	0.490	0.580 (0.402; 0.758)	0.969	0.496 (0.315; 0.678)
Nitrite/nitrate	0.408	0.394 (0.157; 0.630)	0.195	0.649 (0.441; 0.857)	0.755	0.536 (0.337; 0.735)	0.394	0.580 (0.404; 0.757)
8-OHdG	0.258	0.646 (0.397; 0.894)	0.019*	0.770 (0.618; 0.923)	0.908	0.513 (0.289; 0.737)	0.128	0.643 (0.472; 0.814)
FRAP	0.337	0.634 (0.381; 0.887)	0.017*	0.809 (0.677; 0.940)	0.243	0.635 (0.427; 0.843)	0.019*	0.731 (0.568; 0.894)
MDA	0.198	0.680 (0.462; 0.898)	0.013*	0.821 (0.593; 1.000)	0.120	0.680 (0.500; 0.859)	0.007*	0.765 (0.608; 0.922)
Cysteine	0.135	0.708 (0.455; 0.962)	0.007*	0.809 (0.655; 0.963)	0.887	0.483 (0.231; 0.734)	0.074	0.672 (0.494; 0.850)
Homocysteine	0.392	0.619 (0.361; 0.878)	0.025*	0.758 (0.578; 0.938)	0.915	0.487 (0.282; 0.692)	0.221	0.618 (0.445; 0.790)
Cysteinylglycine	0.232	0.667 (0.471; 0.862)	0.130	0.674 (0.439; 0.910)	0.606	0.563 (0.362; 0.764)	0.161	0.635 (0.452; 0.818)
Glutathione	0.765	0.458 (0.124; 0.792)	0.308	0.617 (0.394; 0.841)	0.062	0.727 (0.525; 0.929)	0.660	0.542 (0.346; 0.738)
TIMP1	0.461	0.595 (0.368; 0.822)	0.003*	0.845 (0.724; 0.965)	0.685	0.547 (0.297; 0.796)	0.058	0.679 (0.492; 0.867)
MMP2	0.940	0.510 (0.311; 0.709)	0.219	0.649 (0.382; 0.916)	0.972	0.496 (0.288; 0.704)	0.411	0.580 (0.387; 0.773)
MMP9	0.101	0.861 (0.678; 1.000)	0.117	0.726 (0.477; 0.976)	0.637	0.578 (0.244; 0.912)	0.239	0.657 (0.411; 0.902)