Table 1. Demographic Characteristics of AIS Patients and Controls.
| AIS Patients | P(Controlvs. AIS) | |||||
| Stroke subtype (TOAST) | ||||||
| Control | SVO | LAA | CE | All AIS | ||
| (n = 34) | (n = 42) | (n = 39) | (n = 24) | (n = 105) | ||
| Age, y, mean (SD) | 66 (11) | 64 (9) | 66 (13) | 66 (10) | 65 (11) | 0.88 |
| Male, n (%) | 20 (59) | 24 (57) | 22 (56) | 13 (54) | 59 (56) | 0.94 |
| Diabetes mellitus, n (%) | 4 (12) | 11 (26) | 8 (21) | 8 (33) | 27 (26) | 0.14 |
| Hypertension, n (%) | 8 (24) | 28 (67) | 27 (69) | 15 (63) | 70 (67) | <0.001* |
| Hypercholesterolemia, n (%) | 14 (41) | 16 (38) | 18 (46) | 7 (29) | 41 (39) | 0.98 |
| Smoking, n (%) | 9 (26) | 15 (36) | 11 (28) | 7 (29) | 33 (31) | 0.74 |
| Previous stroke, n (%) | 0 (0) | 10 (24) | 5 (13) | 8 (33) | 23 (22) | 0.007* |
| NIHSS, median (IQR) | 0 (0) | 4.5 (3.0–6.0) | 8.0 (4.0–14.0) | 11.5 (5.0–16.0) | 5.0 (4.0–11.0) | <0.001* |
| Infarct volume (cm3), median (IQR) | NT | 0.7 (0.1–1.4) | 7.2 (2.4–24.1) | 6.0 (3.6–28.9) | 2.7 (0.8–10.1) | NT |
| 3-month mRS, median (IQR) | NT | 1.0 (1.0–2.0) | 1.0 (1.0–2.8) | 3.5 (1.0–5.0) | 1.0 (1.0–3.0) | NT |
AIS, acute ischemic stroke; TOAST, Trial of Org 10172 in Acute Stroke Treatment criteria; SVO, small-vessel occlusion or lacunar; LAA, large artery atherosclerosis or atherothrombosis; CE, cardioembolic; NIHSS, National Institutes of Health Stroke Scale; IQR, interquartile range; NT, not tested; mRS, modified Rankin Scale.
*
P<0.05.