Figure 8. Mtb Δfcr mutants display higher growth rates under in vitro dormancy.

A, Growth (optical density at 600 nm) of Mtb WT, Δfcr mutants and complemented mutants in liquid culture was measured at 0, 3, 6, 9 and 18 days under the MS treatment. B, Viable bacteria were enumerated as CFUs on 7H10-agar plates at 0, 3, 6, 9 and 18 day time points. WT, wild-type; d-fcr1, fcr1-deletion mutant; C-fcr1, complemented fcr1-deletion mutant; d-fcr2, fcr2-deletion mutant; C-fcr2, complemented fcr2-deletion mutant. Average ± standard deviation from three experiments shown (n = 3); p<0.05.