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. 2012 Dec 14;7(12):e48238. doi: 10.1371/journal.pone.0048238

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© 2012 Lee et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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IPA analysis of the top 100 probe-sets from heart and muscle gene clusters (Figure 7) showed the enrichment of calcium signalling pathway. In this figure, we have highlighted the genes present in this pathway in orange. Though this pathway is generalised for skeletal muscle contraction and cardiac muscle contraction, they differ in the members of the same gene family. The heart and muscle genes present in this pathway are given in Tables 7 and 8. Pathway diagram was drawn using Path Designer function of IPA [18].