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Time courses of rate–pressure product (RPP) (a) and relaxation rate (R1) (b) during imaging protocol. Shaded areas indicate the wash-out period. Sodium–calcium (Na+–Ca2+) exchanger (NCX) inhibition was induced by 1 μM SEA0400 during either manganese (Mn2+) perfusion (SEAin) or wash-out (SEAout). *p < 0.05 compared with control (CNTL).
