Table 2.
Frequencies, sensitivity and positive predictive value (PPV) of the selected ICD-9-CM codes and numbers of codes per individual identified through hospital discharge record queries at the University of North Carolina and Seattle Children’s Hospital among patients identified as possibly having craniofacial microsomia (CFM).
| University of North Carolina | Seattle Children’s Hospital | |||||||
|---|---|---|---|---|---|---|---|---|
|
| ||||||||
| Individuals with any of the selected ICD-9-CM codes*
|
Sensitivity | PPV | Individuals with any of the selected ICD-9-CM codes*
|
Sensitivity | PPV | |||
| CFM (N=93) | no-CFM (N=706) | CFM (N=32) | no-CFM (N=468) | |||||
| ICD-9-CM codes** | n (%) | n (%) | % (95% CI) | % (95% CI) | n (%) | n (%) | % (95% CI) | % (95% CI) |
| 744.01 | -- | -- | -- | -- | 6 (19) | 1 (0) | 19 (7–36) | 86 (42–100) |
| 744.02 | 9 (10) | 1 (0) | 10 (5–18) | 90 (56–100) | 9 (28) | 8 (2) | 28 (14–47) | 53 (28–77) |
| 744.09 | 1 (1) | 1 (0) | 1 (0–6) | 50 (1–99) | -- | -- | -- | -- |
| 744.1 | -- | -- | -- | -- | 2 (6) | 15 (3) | 6 (1–21) | 12 (2–36) |
| 744.23 | 76 (82) | 6 (1) | 82 (72–89) | 93 (85–97) | 23 (72) | 5 (1) | 72 (86–53) | 82 (63–94) |
| 744.83 | 5 (5) | 1 (0) | 5 (2–12) | 83 (36–100) | 0 (0) | 2 (0) | -- | -- |
| 754.0 | 33 (36) | 664 (94) | 36 (26–46) | 5 (3–7) | 1 (3) | 254 (54) | 3 (0–16) | <1 (0–2) |
| 756.0 | 17 (18) | 48 (7) | 18 (11–28) | 26 (16–39) | 12 (38) | 209 (45) | 38 (21–56) | 5 (3–9) |
| Combination of codes** | ||||||||
| 744.01 & 744.02 | 0 (0) | n.a. | -- | -- | 2 (6) | n.a. | 6 (1–21) | 67 (9–99) |
| 744.01 & 744.23 | 0 (0) | n.a. | -- | -- | 5 (16) | n.a. | 16 (5–33) | 100 (48–100) |
| 744.01 & 756.0 | 0 (0) | n.a. | -- | -- | 3 (9) | n.a. | 9 (2–25) | 75 (19–99) |
| 744.02 & 744.1 | 0 (0) | n.a. | -- | -- | 1 (3) | n.a. | 3 (0–16) | 100 (3–100) |
| 744.02 & 744.23 | 6 (7) | n.a. | 7 (2–14) | 86 (42–100) | 9 (28) | n.a. | 28 (14–47) | 90 (56–100) |
| 744.02 & 744.83 | 1 (1) | n.a. | 1 (0–6) | 100 (3–100) | 0 (0) | n.a. | -- | -- |
| 744.02 & 754.0 | 4 (4) | n.a. | 4 (1–11) | 100 (40–100) | 0 (0) | n.a. | -- | -- |
| 744.02 & 756.0 | 4 (4) | n.a. | 4 (1–11) | 100 (40–100) | 3 (9) | n.a. | 9 (2–25) | 75 (19–99) |
| 744.1 & 744.23 | 0 (0) | n.a. | -- | -- | 2 (6) | n.a. | 6 (1–21) | 67 (9–99) |
| 744.1 & 756.0 | 0 (0) | n.a. | -- | -- | 1 (3) | n.a. | 3 (0–16) | 50 (1–99) |
| 744.23 & 744.83 | 3 (3) | n.a. | 3 (1–9) | 100 (29–100) | 0 (0) | n.a. | -- | -- |
| 744.23 & 754.0 | 21 (23) | n.a. | 23 (15–32) | 96 (77–100) | 0 (0) | n.a. | -- | -- |
| 744.23 & 756.0 | 10 (11) | n.a. | 11 (5–19) | 77 (46–95) | 5 (16) | n.a. | 16 (5–33) | 83 (36–100) |
| 744.83 & 754.0 | 2 (2) | n.a. | 2 (0–8) | 100 (16–100) | 0 (0) | n.a. | -- | -- |
| 744.83 & 756.0 | 2 (2) | n.a. | 2 (0–8) | 100 (16–100) | 0 (0) | n.a. | -- | -- |
| 754.0 & 756.0 | 8 (9) | n.a. | 9 (4–16) | 47 (23–72) | 0 (0) | n.a. | -- | -- |
| Number of codes per individual | ||||||||
| 1 | 55 (59) | 692 (98) | n.a. | n.a. | 19 (59) | 444 (95) | n.a. | n.a. |
| 2 | 30 (32) | 13 (2) | n.a. | n.a. | 7 (22) | 22 (5) | n.a. | n.a. |
| 3 | 7 (8) | 1 (0) | n.a. | n.a. | 4 (13) | 2 (0) | n.a. | n.a. |
| >=4 | 1 (1) | -- | n.a. | n.a. | 2 (6) | 0 (0) | n.a. | n.a. |
n.a.: not applicable
CI: Confidence Interval
*
There were no participants assigned with the ICD-9-CM codes: 743.8 744.0, and 744.21 either at UNC or SCH.
**
Numbers do not add up to the totals because all possible two CFM-codes are shown, ie, if an individual had 3 codes assigned there are three possible pairwise combinations, so that individual is listed three times.