Table I.
Patient Characteristics
| Patients enrolled | 33 |
| Evaluable patients | 31 |
| Male : Female | 18 : 13 |
| Median age (range in years) | 12 (2–19) |
| Median courses per patient (range) | 1 (1–4) |
| Performance status (Karnofsky or Lansky play score) | |
| 50 | 3 (10%) |
| 70 | 1 (3%) |
| 80 | 6 (19%) |
| 90 | 8 (26%) |
| 100 | 13 (42%) |
| Prior therapy | |
| Chemotherapy | 28 (90%) |
| Radiation therapy | 17 (55%) |
| Surgery | 29 (94%) |
| Immunotherapy | 7 (23%) |
| Hormonal therapy | 0 |
| Tumor types | |
| CNS1 | 11 (35%) |
| Hepatoblastoma | 4 (13%) |
| Sarcoma | 11 (35%) |
| Other2 | 5 (16%) |
1
Tumor types included ependymoma(3), medulloblastoma (2), chordoma (2), one patient each with diffuse pontine glioma, high grade glioma and atypical teratoid/rhabdoid tumor (AT/RT) and one with tumor not otherwise specified (NOS);
2
One patient each with carcinoid, lymphoepithelioma, adenocarcinoma of the liver, hepatocellular carcinoma, and neuroblastoma