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Efficacy endpoints in all patients receiving prophylactic LMWH or fondaparinux for thromboprophylaxis after major orthopaedic surgery (95% Blyth-Still-Casella confidence intervals)
| LMWH n= 1495 | Fondaparinux n= 1994 | ||||
|---|---|---|---|---|---|
| Efficacy endpoints | % (n) | 95% CI | % (n) | 95% CI | P value |
| All VTE | 4.15 (62) | 3.19–5.23 | 5.62 (112) | 4.67–6.68 | 0.047 |
| Proximal DVT | 1.07 (16) | 0.64–1.69 | 1.30 (26) | 0.85–1.87 | 0.639 |
| PE | 0.54 (8) | 0.23–1.03 | 0.50 (10) | 0.27–0.89 | 0.999 |
| Distal VTE | 2.47 (37) | 1.78–3.37 | 3.91 (78) | 3.10–4.83 | 0.021 |
