Table 1.
Systemic antibiotics used during pregnancy (n= 180 120 women)*
| First trimester | Second and third trimester | First–third trimester | |
|---|---|---|---|
| Oral antibiotic | n (%) | n (%) | n (%) |
| Macrolides | 2549 (1.4) | 4437 (2.5) | 6744 (3.7) |
| Erythromycin | 1786 (1.0) | 4122 (2.3) | 5729 (3.2) |
| Azitromycin | 643 (0.4) | 280 (0.2) | 913 (0.5) |
| Clarithromycin | 229 (0.1) | 77 (0.04) | 304 (0.2) |
| Spiramycin | 33 (0.02) | 86 (0.05) | 116 (0.1) |
| Penicillins | 12 049 (6.7) | 31 360 (17.4) | 39 658 (22.0) |
| Penicillin V | 4921 (2.7) | 12 477 (6.9) | 16 695 (9.3) |
| Amoxicillin | 1599 (0.9) | 5445 (3.0) | 6824 (3.8) |
| Nitrofurantoin | 1334 (0.7) | 4714 (2.6) | 5794 (3.2) |
| Sulfonamide/trimetoprim | 924 (0.5) | 2512 (1.4) | 3398 (1.9) |
| Tetracyclines | 651 (0.4) | 65 (0.04) | 712 (0.4) |
| Cefalosporines | 201 (0.1) | 521 (0.3) | 710 (0.4) |
| Fluoroquinolones | 114 (0.1) | 33 (0.02) | 147 (0.1) |
*
The use of one or more courses of the same antibiotics was counted once; the use of different antibiotics was counted as one per course.