Table 2. Fixed-effects coefficients from linear mixed-effects model.

Coefficient	VCC RNFLT		ECC RNFLT		OCT RNFLT		SAP MD
	Estimate	P	Estimate	P	Estimate	P	Estimate	P
Rate of change in controls (β3) (μm per year)	−0.4	0.01	−0.3	0.01	0.6	0.19	0.03 (dB per year)	0.68
Difference in rate of change (β4) (μm per year)	0.2	0.31	0.2	0.19	−0.6	0.32	−0.23 (dB per year)	0.01
Mean baseline in controls (β1) (μm)	50.6	<0.001	49.5	<0.001	100.1	<0.001	0.14 (dB)	0.84
Difference in mean baseline (β2) (μm)	−10.3	<0.001	−10.3	<0.001	−31.1	<0.001	−4.30 (dB)	<0.001
Baseline age (β5) (μm per year)	−0.1	0.04	−0.1	0.22	−0.2	0.12	−0.11 (dB per year)	<0.01
TSS (β6) (μm/U score)	−0.2	<0.001	−0.2	<0.001	N/A	N/A	N/A	N/A

Abbreviations: ECC, enhanced corneal compensation; MD, mean deviation; OCT, optical coherence tomography; RNFLT, retinal nerve fibre layer thickness; SAP, standard automated perimetry; VCC, variable corneal compensation.

Values shown are fixed effects with coefficients from Equations 1, 2, 3 indicated. Rows in bold indicate the estimates of effects relating to the rate of change in control subjects (β₃), and the difference between the rate of change in the controls and the glaucoma patients (β₄). The mean rate of change in the glaucoma patients is given by β₃+β₄.