Table 3. Reports of RNFL thickness values measured by OCT in large studies (n>100).
| Paper | OCT | OCT type | Country | N | Age mean (range), years | Average RNFL, μm | Temporal RNFL, μm | Superior RNFL, μm | Nasal RNFL, μm | Inferior RNFL, μm |
|---|---|---|---|---|---|---|---|---|---|---|
| Current study | Cirrus | SD | Australia | 1521 | 17.3 (16–19) | 99.4±9.7 | 69.8±11.5 | 124.8±15.9 | 74.3±12.6 | 128.5±17.2 |
| Knight et al16 | Cirrus | SD | USA | 271 | 46.2 (18 -84) | 94.0 SE:0.6 | 64.0 SE:0.6 | 119.0 SE:0.9 | 69.8 SE:0.7 | 123.2 SE:1.0 |
| Hong et al17 | Cirrus | SD | Korea | 269 | 21.3 (19–26) | 98.6±8.7 | ||||
| Girkin et al19 | RTVue | SD | USAa | 219 | 53.4 | 101.9±9.8 | ||||
| Hirasawa et al27 | Topcon | SD | Japan | 251 | ≥20 | 101.9±8.4 | 78.6±13.3 | 123.9±13.6 | 79.6±13.6 | 125.5±13.1 |
| Bendschneider et al26 | Spectralis | SD | Germany | 170 | ∼20–79 | 97.2±9.7 | 68.8±11.1 | 118.0±14.5 | 76.4±15.0 | 123.7±16.4 |
| Turk et al20 | Spectralis | SD | Turkey | 107 | 10.5 (6–16) | 106.5±9.4 | ||||
| Huynh et al22 | Stratus | TD | Australia | 2132 | (11.1–14.4) | 103.6±10.6 | 74.6±12.8 | 129.7±17.5 | 82.0±16.7 | 128.3±18.6 |
| Huynh et al9 | Stratus | TD | Australia | 1369 | 6.7 | 103.7±11.4 | 75.7±14.7 | 129.5±20.6 | 81.7±19.6 | 127.8±20.5 |
| El Dairi et al10 | Stratus | TD | USA | 286 | 8.6 (3–17) | 108 (92–125) | 78 (56–105) | 143 (112–177) | 83 (56–120) | 129 (102–160) |
| Budenz et al7 | Stratus | TD | USA | 328 | 47.4 (18–85) | 100.1±11.6 | 69.0±12.7 | 124.2±17.9 | 80.9±18.1 | 126.1±17.8 |
Abbreviations: RNFL, retinal nerve fiber layer; SD, spectral domain; SE, standard error; TD, time domain.
a
European descent.