Table 3.
Mean Specific Binding of [3H]SCH 23390 to D1 receptors and [3H]Spiperone to D2 receptors and Ratio of D2:D1 receptors in Rats
D1 binding | D2 binding | D2:D1 Ratio | |
---|---|---|---|
CPu | 685.12 ± 33.88 | 146.67 ± 12.42 | 0.212 ± 0.010 |
ACb.c | 611.21 ± 36.39 | 87.34 ± 8.93 | 0.148 ± 0.020 |
ACb.s | 748.74 ± 43.83 | 91.51 ± 9.65 | 0.127 ± 0.017 |
Tu | 755.74 ± 50.82 | 110.82 ± 11.58 | 0.147 ± 0.014 |
mPOA | 11.23 ± 7.27 | 7.907 ± 5.43 | 0.663 ± 0.082 |
All values are mean fmol/mg of tissue ± 1 SE, n=8 per group except mPOA where n=7.
CPu, caudate putamen; ACb.c, nucleus accumbens core; ACb.s, nucleus accumbens shell; Tu, olfactory tubercle; mPOA, medial preoptic area.