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. Author manuscript; available in PMC: 2013 Sep 17.
Published in final edited form as: Angew Chem Int Ed Engl. 2012 Aug 22;51(38):9562–9566. doi: 10.1002/anie.201205137

Table 1.

Optimization of the catalytic system.

graphic file with name nihms415545u1.jpg
Entry Conditions[a] t [h] Conv. of 5a [%][b] Yield of 6a [%][b]
1 4a (2 mol%), CH3CN 24 44 31
2 4a (2 mol%), CH3CN, O2 24 49 33
3 4a (2 mol%), TFE 24 42 21
4 4a (2 mol%), silica gel, CH3CN 12 100 68
5 4a (4 mol%), silica gel, CH3CN 5 100 88
6 4b (2 mol%), silica gel, CH3CN 24 100 19
7 Silica gel, CH3CN, no 4a, light 24 8 4
8 4a (2 mol%), silica gel, CH3CN, no light 24 4 2
9 4a (2 mol%), silica gel, CH3CN, degassed 24 8 0
[a]

Conditions: 5a (0.2 mmol), solvent, open air, irradiation with a white LED light at rt.

[b]

Measured by GC using dodecane as an internal standard.